To avoid taking a bath, Fister Farnello runs away from home and is befriended by Dirt Man, a filthy giant who lives in the woods.

Angry with her mother, twelve-year-old runaway Ren finds an unusual boarding house in a nearby ghost town, Fortune, where she meets some interesting people and learns of a forgotten treasure from when the town was famous for buttons made of Mississippi River shells.

Little Rabbit gets scolded so often he decides to run away and build his very own home.

When an unhappy young pig decides to run away, his mother helps him to see that everything he needs and wants is right there at home.

In England in 1346 Adrian has three problems: he is small for his twelve years, he is an albino, so people are suspicious of him, and his father wants him to be a scribe, while he wants to be an archer--but when he runs away to join his friend in the fight against the invading Scots, he learns that war can be a lot more complicated then he imagined.

When his mother gets angry over the mess he has made and he decides to run away with his friend, Blackboard Bear, Anthony discovers that the woods can be a very scary place.

Tired of being ignored by his human family, Chester the dog sets off to find a new home, but when he is turned away by a flock of forest birds and taken in by a wealthy woman who treats him more like a toy than a dog, Chester soon discovers that old homes are not so easily replaced.

In 1939, after cruel treatment at her orphanage renders her mute, Lucy runs away and joins the circus, working with the elephants and unaware that the orphanage matrons are hunting for her.

In 1904, twelve-year-old Orphelia follows her dream by running away from home to join an all-black minstrel show headed for the Saint Louis World's Fair, and learns about her family's troubled past in the process.